CatalogueNumber: | AN00007 |
ProductName: | anti-5Lipoxygenaseantibody |
Form: | liquid |
Host: | Rabbit |
Clonity: | polyclonal |
Isotope: | IgG |
Storage: | PBSwith0.02%sodiumazideand50%glycerolpH7.3,-20â&BDquo;ƒfor24months(Avoidrepeatedfreeze/thawcycles.) |
Background: | ALOX5(arachidonate5-lipoxygenase)isalsonamedasLOG5,5-LOandbelongstothelipoxygenasefamily.Itcatalyzesthefirststepinleukotrienebiosynthesis,andplaysaroleininflammatoryprocesses.Itisa78kDairon-containingenzymethattranslocatesfromthecytosoltoassociatewithFLAP,andconvertsarachidonateintwostepsintotheunstableintermediateLTA4.Itisessentialforcysteinyl-leukotriene(cys-LT)production,criticalmediatorsinasthma(PMID:12911785). |
Immunogen: | arachidonate5-lipoxygenase |
Synonyms: | 5Lipoxygenase,5LO,5LOX,5LPG,ALOX5,LOG5 |
CalculatedMW: | 75kDa |
Specificity: | Human,Mouse |
TestedApplication: | ELISA,IF,WB |
RecommendedDilution: | WB:1:200-1:2000;IF:1:20-1:100 |
WBDilution: | HL-60cellsweresubjectedtoSDSPAGEfollowedbywesternblotwithALOX5Antibodyatdilutionof1:600 |
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